Vhf07504 details

Gene vhfRNAi AccessionVhf07504
Gene SymbolAHI1
Gene DescriptionJouberin (Abelson helper integration site 1 protein homolog) (AHI-1)
Gene Name in PaperAHI1
GroupHost Factor
Ensembl Gene IDENST00000265602 ENST00000327035 ENST00000367800 ENST00000457866 ENST00000531788 
UniProt IDQ8N157
Entrez Gene ID54806
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)