RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07488 |
| Gene Symbol | NOP2 | |
| Gene Description | Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120) | |
| Gene Name in Paper | NOP2 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000322166 ENST00000382421 ENST00000399466 ENST00000537442 ENST00000541778 ENST00000545200 ENST00000617555 ENST00000620535 | |
| UniProt ID | P46087 | |
| Entrez Gene ID | 4839 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |