Vhf07455 details

Gene vhfRNAi AccessionVhf07455
Gene SymbolEPGN
Gene DescriptionEpigen (Epithelial mitogen) (EPG)
Gene Name in PaperEPGN
GroupHost Factor
Ensembl Gene IDENST00000332112 ENST00000413830 ENST00000502358 ENST00000503098 ENST00000505212 ENST00000509145 ENST00000514968 
UniProt IDQ6UW88
Entrez Gene ID255324
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)