RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf07429 |
Gene Symbol | RU17 | |
Gene Description | U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70) | |
Gene Name in Paper | RU17 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000221448 ENST00000401730 ENST00000595231 ENST00000598441 ENST00000601065 | |
UniProt ID | P08621 | |
Entrez Gene ID | 6625 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |