RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07408 |
| Gene Symbol | APC11 | |
| Gene Description | Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein) | |
| Gene Name in Paper | APC11 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000344877 ENST00000357385 ENST00000392376 ENST00000571024 ENST00000571570 ENST00000571874 ENST00000572639 ENST00000572851 ENST00000574924 ENST00000575195 ENST00000577747 ENST00000578550 ENST00000579978 ENST00000583839 | |
| UniProt ID | Q9NYG5 | |
| Entrez Gene ID | 51529 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |