Vhf07394 details

Gene vhfRNAi AccessionVhf07394
Gene SymbolACBD4
Gene DescriptionAcyl-CoA-binding domain-containing protein 4
Gene Name in PaperACBD4
GroupHost Factor
Ensembl Gene IDENST00000321854 ENST00000376955 ENST00000398322 ENST00000431281 ENST00000586346 ENST00000591859 ENST00000619916 
UniProt IDQ8NC06
Entrez Gene ID79777
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)