Vhf07386 details

Gene vhfRNAi AccessionVhf07386
Gene SymbolMYPN
Gene DescriptionMyopalladin (145 kDa sarcomeric protein)
Gene Name in PaperMYPN
GroupHost Factor
Ensembl Gene IDENST00000354393 ENST00000358913 ENST00000373675 ENST00000540630 
UniProt IDQ86TC9
Entrez Gene ID84665
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)