RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07337 |
| Gene Symbol | APBB3 | |
| Gene Description | Amyloid beta A4 precursor protein-binding family B member 3 (Protein Fe65-like 2) (Fe65L2) | |
| Gene Name in Paper | APBB3 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000354402 ENST00000356738 ENST00000357560 ENST00000412920 ENST00000467078 ENST00000509914 | |
| UniProt ID | O95704 | |
| Entrez Gene ID | 10307 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |