Vhf07323 details

Gene vhfRNAi AccessionVhf07323
Gene SymbolGCC1
Gene DescriptionGRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1)
Gene Name in PaperGCC1
GroupHost Factor
Ensembl Gene IDENST00000321407 
UniProt IDQ96CN9
Entrez Gene ID79571
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)