Vhf07312 details

Gene vhfRNAi AccessionVhf07312
Gene SymbolFA49B
Gene DescriptionProtein FAM49B (L1)
Gene Name in PaperFA49B
GroupHost Factor
Ensembl Gene IDENST00000401979 ENST00000517654 ENST00000519110 ENST00000519540 ENST00000519824 ENST00000522250 ENST00000522746 ENST00000522941 ENST00000523509 
UniProt IDQ9NUQ9
Entrez Gene ID51571
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)