Vhf07310 details

Gene vhfRNAi AccessionVhf07310
Gene SymbolRUFY2
Gene DescriptionRUN and FYVE domain-containing protein 2 (Rab4-interacting protein related)
Gene Name in PaperRUFY2
GroupHost Factor
Ensembl Gene IDENST00000388768 ENST00000399200 ENST00000454950 ENST00000602465 
UniProt IDQ8WXA3
Entrez Gene ID55680
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)