RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf07282 |
Gene Symbol | GTPB3 | |
Gene Description | tRNA modification GTPase GTPBP3, mitochondrial (GTP-binding protein 3) (Mitochondrial GTP-binding protein 1) | |
Gene Name in Paper | GTPB3 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000324894 ENST00000358792 ENST00000361619 ENST00000600625 | |
UniProt ID | Q969Y2 | |
Entrez Gene ID | 84705 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |