RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07255 |
| Gene Symbol | SMCA4 | |
| Gene Description | Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4) | |
| Gene Name in Paper | SMCA4 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000344626 ENST00000429416 ENST00000444061 ENST00000541122 ENST00000589677 ENST00000590574 | |
| UniProt ID | P51532 | |
| Entrez Gene ID | 6597 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |