Vhf07253 details

Gene vhfRNAi AccessionVhf07253
Gene SymbolOPALI
Gene DescriptionOpalin (Oligodendrocytic myelin paranodal and inner loop protein) (Transmembrane protein 10)
Gene Name in PaperOPALI
GroupHost Factor
Ensembl Gene IDENST00000371172 ENST00000393871 ENST00000419479 ENST00000611913 
UniProt IDQ96PE5
Entrez Gene ID93377
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)