Vhf07219 details

Gene vhfRNAi AccessionVhf07219
Gene SymbolAKNA
Gene DescriptionAT-hook-containing transcription factor
Gene Name in PaperAKNA
GroupHost Factor
Ensembl Gene IDENST00000223791 ENST00000307564 ENST00000312033 ENST00000374075 ENST00000374079 ENST00000374088 
UniProt IDQ7Z591
Entrez Gene ID80709
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)