Vhf07212 details

Gene vhfRNAi AccessionVhf07212
Gene SymbolELOC
Gene DescriptionTranscription elongation factor B polypeptide 1 (Elongin 15 kDa subunit) (Elongin-C) (EloC) (RNA polymerase II transcription factor SIII subunit C) (SIII p15)
Gene Name in PaperELOC
GroupHost Factor
Ensembl Gene IDENST00000284811 ENST00000518127 ENST00000519487 ENST00000520210 ENST00000520242 ENST00000522337 ENST00000523815 ENST00000622804 
UniProt IDQ15369
Entrez Gene ID6921
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)