Vhf07208 details

Gene vhfRNAi AccessionVhf07208
Gene SymbolNP1L1
Gene DescriptionNucleosome assembly protein 1-like 1 (NAP-1-related protein) (hNRP)
Gene Name in PaperNP1L1
GroupHost Factor
Ensembl Gene IDENST00000261182 ENST00000393263 ENST00000431879 ENST00000549596 ENST00000618691 
UniProt IDP55209
Entrez Gene ID4673
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)