Vhf07207 details

Gene vhfRNAi AccessionVhf07207
Gene SymbolTMPS7
Gene DescriptionTransmembrane protease serine 7 (EC 3.4.21.-) (Matriptase-3)
Gene Name in PaperTMPS7
GroupHost Factor
Ensembl Gene IDENST00000419127 ENST00000452346 ENST00000617607 
UniProt IDQ7RTY8
Entrez Gene ID344805
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)