Vhf07175 details

Gene vhfRNAi AccessionVhf07175
Gene SymbolCAPG
Gene DescriptionMacrophage-capping protein (Actin regulatory protein CAP-G)
Gene Name in PaperCAPG
GroupHost Factor
Ensembl Gene IDENST00000263867 ENST00000409670 ENST00000409724 ENST00000409921 
UniProt IDP40121
Entrez Gene ID822
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)