Vhf07163 details

Gene vhfRNAi AccessionVhf07163
Gene SymbolTX264
Gene DescriptionTestis-expressed sequence 264 protein (Putative secreted protein Zsig11)
Gene Name in PaperTX264
GroupHost Factor
Ensembl Gene IDENST00000341333 ENST00000395057 ENST00000415259 ENST00000416589 ENST00000457573 ENST00000611400 
UniProt IDQ9Y6I9
Entrez Gene ID51368
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)