RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf07157 |
Gene Symbol | DICER | |
Gene Description | Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI) | |
Gene Name in Paper | DICER | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000343455 ENST00000393063 ENST00000526495 ENST00000527414 ENST00000541352 ENST00000556045 | |
UniProt ID | Q9UPY3 | |
Entrez Gene ID | 23405 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |