RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07155 |
| Gene Symbol | SHBG | |
| Gene Description | Sex hormone-binding globulin (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estradiol-binding globulin) (TeBG) (Testosterone-estrogen-binding globulin) | |
| Gene Name in Paper | SHBG | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000380450 ENST00000416273 ENST00000441599 ENST00000575903 | |
| UniProt ID | P04278 | |
| Entrez Gene ID | 6462 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |