Vhf07119 details

Gene vhfRNAi AccessionVhf07119
Gene SymbolPP1R7
Gene DescriptionProtein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)
Gene Name in PaperPP1R7
GroupHost Factor
Ensembl Gene IDENST00000234038 ENST00000272983 ENST00000401987 ENST00000402734 ENST00000406106 ENST00000407025 
UniProt IDQ15435
Entrez Gene ID5510
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)