RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07062 |
| Gene Symbol | DDR1 | |
| Gene Description | Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) | |
| Gene Name in Paper | DDR1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000259875 ENST00000324771 ENST00000376567 ENST00000376568 ENST00000376569 ENST00000376570 ENST00000376575 ENST00000383377 ENST00000400410 ENST00000400411 ENST00000400414 ENST00000400486 ENST00000400488 ENST00000400489 ENST00000400491 ENST00000400492 ENST00000412329 ENST00000415092 ENST00000418800 ENST00000419412 ENST00000421229 ENST00000427053 ENST00000429699 ENST00000430933 ENST00000449518 ENST00000452441 ENST00000453510 ENST00000454612 ENST00000454774 ENST00000482873 ENST00000508312 ENST00000513240 ENST00000548133 ENST00000548962 ENST00000549026 ENST00000550384 ENST00000550395 ENST00000552068 ENST00000552721 ENST00000553015 ENST00000617572 ENST00000618059 ENST00000620318 ENST00000621544 | |
| UniProt ID | Q08345 | |
| Entrez Gene ID | 780 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |