Vhf07054 details

Gene vhfRNAi AccessionVhf07054
Gene SymbolSYT2
Gene DescriptionSynaptotagmin-2 (Synaptotagmin II) (SytII)
Gene Name in PaperSYT2
GroupHost Factor
Ensembl Gene IDENST00000367267 ENST00000367268 
UniProt IDQ8N9I0
Entrez Gene ID127833
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)