Vhf07053 details

Gene vhfRNAi AccessionVhf07053
Gene SymbolTAU
Gene DescriptionMicrotubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene Name in PaperTAU
GroupHost Factor
Ensembl Gene IDENST00000262410 ENST00000334239 ENST00000340799 ENST00000344290 ENST00000351559 ENST00000415613 ENST00000420682 ENST00000431008 ENST00000446361 ENST00000535772 ENST00000571987 ENST00000574436 ENST00000612872 ENST00000613360 ENST00000620070 ENST00000620818 ENST00000620981 ENST00000621329 ENST00000622106 ENST00000622728 ENST00000626571 ENST00000628393 ENST00000631447 ENST00000632500 ENST00000633047 ENST00000634049 
UniProt IDP10636
Entrez Gene ID4137
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)