Vhf07033 details

Gene vhfRNAi AccessionVhf07033
Gene SymbolLYSM1
Gene DescriptionLysM and putative peptidoglycan-binding domain-containing protein 1
Gene Name in PaperLYSM1
GroupHost Factor
Ensembl Gene IDENST00000368908 ENST00000440902 
UniProt IDQ96S90
Entrez Gene ID388695
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)