Vhf07014 details

Gene vhfRNAi AccessionVhf07014
Gene SymbolBCAR1
Gene DescriptionBreast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene Name in PaperBCAR1
GroupHost Factor
Ensembl Gene IDENST00000162330 ENST00000393420 ENST00000393422 ENST00000418647 ENST00000420641 ENST00000535626 ENST00000538440 ENST00000542031 
UniProt IDP56945
Entrez Gene ID9564
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)