RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf06958 |
Gene Symbol | OGDHL | |
Gene Description | 2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.-) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) (Alpha-ketoglutarate dehydrogenase-like) | |
Gene Name in Paper | OGDHL | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000374103 ENST00000419399 ENST00000432695 | |
UniProt ID | Q9ULD0 | |
Entrez Gene ID | 55753 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |