Vhf06897 details

Gene vhfRNAi AccessionVhf06897
Gene SymbolPRR5
Gene DescriptionProline-rich protein 5 (Protein observed with Rictor-1) (Protor-1)
Gene Name in PaperPRR5
GroupHost Factor
Ensembl Gene IDENST00000006251 ENST00000336985 ENST00000403581 ENST00000611394 ENST00000617066 ENST00000624862 
UniProt IDP85299
Entrez Gene ID55615
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)