Vhf06886 details

Gene vhfRNAi AccessionVhf06886
Gene SymbolRAB34
Gene DescriptionRas-related protein Rab-34 (Ras-related protein Rab-39) (Ras-related protein Rah)
Gene Name in PaperRAB34
GroupHost Factor
Ensembl Gene IDENST00000301043 ENST00000395243 ENST00000395245 ENST00000415040 ENST00000436730 ENST00000450529 
UniProt IDQ9BZG1
Entrez Gene ID83871
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)