Vhf06879 details

Gene vhfRNAi AccessionVhf06879
Gene SymbolFGF1
Gene DescriptionFibroblast growth factor 1 (FGF-1) (Acidic fibroblast growth factor) (aFGF) (Endothelial cell growth factor) (ECGF) (Heparin-binding growth factor 1) (HBGF-1)
Gene Name in PaperFGF1
GroupHost Factor
Ensembl Gene IDENST00000337706 ENST00000359370 ENST00000360966 ENST00000378046 ENST00000419524 ENST00000441680 ENST00000610990 ENST00000612258 ENST00000619447 ENST00000621536 
UniProt IDP05230
Entrez Gene ID2246
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)