RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf06879 |
Gene Symbol | FGF1 | |
Gene Description | Fibroblast growth factor 1 (FGF-1) (Acidic fibroblast growth factor) (aFGF) (Endothelial cell growth factor) (ECGF) (Heparin-binding growth factor 1) (HBGF-1) | |
Gene Name in Paper | FGF1 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000337706 ENST00000359370 ENST00000360966 ENST00000378046 ENST00000419524 ENST00000441680 ENST00000610990 ENST00000612258 ENST00000619447 ENST00000621536 | |
UniProt ID | P05230 | |
Entrez Gene ID | 2246 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |