Vhf06871 details

Gene vhfRNAi AccessionVhf06871
Gene SymbolRN19A
Gene DescriptionE3 ubiquitin-protein ligase RNF19A (EC 6.3.2.-) (Double ring-finger protein) (Dorfin) (RING finger protein 19A) (p38)
Gene Name in PaperRN19A
GroupHost Factor
Ensembl Gene IDENST00000341084 ENST00000519449 ENST00000616528 
UniProt IDQ9NV58
Entrez Gene ID25897
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)