RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf06843 |
Gene Symbol | MBOA7 | |
Gene Description | Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (1-acylglycerophosphatidylinositol O-acyltransferase) (EC 2.3.1.n4) (Bladder and breast carcinoma-overexpressed gene 1 protein) (Leukocyte receptor cluster member 4) (Lysophosphatidylinositol acyltransferase) (LPIAT) (Lyso-PI acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) (h-mboa-7) | |
Gene Name in Paper | MBOA7 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000245615 ENST00000338624 ENST00000391754 ENST00000431666 ENST00000610862 ENST00000611239 ENST00000611602 ENST00000612053 ENST00000612567 ENST00000613506 ENST00000613746 ENST00000614279 ENST00000615282 ENST00000615453 ENST00000617012 ENST00000617656 ENST00000617772 ENST00000618378 ENST00000618826 ENST00000618899 ENST00000619670 ENST00000619745 ENST00000619842 ENST00000619855 ENST00000620311 ENST00000620371 ENST00000620636 ENST00000621146 ENST00000621455 ENST00000621612 ENST00000621875 | |
UniProt ID | Q96N66 | |
Entrez Gene ID | 79143 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |