Vhf06838 details

Gene vhfRNAi AccessionVhf06838
Gene SymbolRASF7
Gene DescriptionRas association domain-containing protein 7 (HRAS1-related cluster protein 1)
Gene Name in PaperRASF7
GroupHost Factor
Ensembl Gene IDENST00000397582 ENST00000397583 ENST00000431809 ENST00000454668 ENST00000622905 
UniProt IDQ02833
Entrez Gene ID8045
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)