Vhf06836 details

Gene vhfRNAi AccessionVhf06836
Gene SymbolNIPA2
Gene DescriptionMagnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2)
Gene Name in PaperNIPA2
GroupHost Factor
Ensembl Gene IDENST00000337451 ENST00000359727 ENST00000398013 ENST00000398014 ENST00000539711 
UniProt IDQ8N8Q9
Entrez Gene ID81614
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)