Vhf06826 details

Gene vhfRNAi AccessionVhf06826
Gene SymbolZN580
Gene DescriptionZinc finger protein 580 (LDL-induced EC protein)
Gene Name in PaperZN580
GroupHost Factor
Ensembl Gene IDENST00000325333 ENST00000543039 ENST00000545125 
UniProt IDQ9UK33
Entrez Gene ID51157
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)