Vhf06820 details

Gene vhfRNAi AccessionVhf06820
Gene SymbolFINC
Gene DescriptionFibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene Name in PaperFINC
GroupHost Factor
Ensembl Gene IDENST00000323926 ENST00000336916 ENST00000354785 ENST00000356005 ENST00000357867 ENST00000359671 ENST00000421182 ENST00000426059 ENST00000432072 ENST00000443816 ENST00000446046 
UniProt IDP02751
Entrez Gene ID2335
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)