RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06817 |
| Gene Symbol | MRE11 | |
| Gene Description | Double-strand break repair protein MRE11A (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A) | |
| Gene Name in Paper | MRE11 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000323929 ENST00000323977 ENST00000407439 | |
| UniProt ID | P49959 | |
| Entrez Gene ID | 4361 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |