Vhf06812 details

Gene vhfRNAi AccessionVhf06812
Gene SymbolPPCEL
Gene DescriptionProlyl endopeptidase-like (EC 3.4.21.-) (Prolylendopeptidase-like)
Gene Name in PaperPPCEL
GroupHost Factor
Ensembl Gene IDENST00000260648 ENST00000378511 ENST00000378520 ENST00000409272 ENST00000409411 ENST00000409936 ENST00000409957 ENST00000410081 ENST00000425263 ENST00000426481 ENST00000541738 
UniProt IDQ4J6C6
Entrez Gene ID9581
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)