RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06799 |
| Gene Symbol | TAF1C | |
| Gene Description | TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C) | |
| Gene Name in Paper | TAF1C | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000341690 ENST00000541676 ENST00000566732 ENST00000567759 ENST00000570117 | |
| UniProt ID | Q15572 | |
| Entrez Gene ID | 9013 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |