Vhf06781 details

Gene vhfRNAi AccessionVhf06781
Gene SymbolK226L
Gene DescriptionUncharacterized protein KIAA0226-like
Gene Name in PaperK226L
GroupHost Factor
Ensembl Gene IDENST00000378784 ENST00000378787 ENST00000389908 ENST00000429979 ENST00000631139 
UniProt IDQ9H714
Entrez Gene ID80183
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)