RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06776 |
| Gene Symbol | SMAD3 | |
| Gene Description | Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3) | |
| Gene Name in Paper | SMAD3 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000327367 ENST00000439724 ENST00000537194 ENST00000540846 | |
| UniProt ID | P84022 | |
| Entrez Gene ID | 4088 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |