Vhf06743 details

Gene vhfRNAi AccessionVhf06743
Gene SymbolR3HD1
Gene DescriptionR3H domain-containing protein 1
Gene Name in PaperR3HD1
GroupHost Factor
Ensembl Gene IDENST00000264160 ENST00000409478 ENST00000409606 ENST00000410054 ENST00000628915 
UniProt IDQ15032
Entrez Gene ID23518
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)