Vhf06729 details

Gene vhfRNAi AccessionVhf06729
Gene SymbolMINT
Gene DescriptionMsx2-interacting protein (SMART/HDAC1-associated repressor protein) (SPEN homolog)
Gene Name in PaperMINT
GroupHost Factor
Ensembl Gene IDENST00000375759 
UniProt IDQ96T58
Entrez Gene ID23013
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)