RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06721 |
| Gene Symbol | IKBL1 | |
| Gene Description | NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1) | |
| Gene Name in Paper | IKBL1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000376148 ENST00000383500 ENST00000400279 ENST00000400285 ENST00000414391 ENST00000419122 ENST00000419623 ENST00000421396 ENST00000424652 ENST00000428467 ENST00000430501 ENST00000430961 ENST00000432160 ENST00000434332 ENST00000442947 ENST00000451911 ENST00000453377 ENST00000455376 ENST00000456607 | |
| UniProt ID | Q9UBC1 | |
| Entrez Gene ID | 4795 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |