RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06719 |
| Gene Symbol | GRIA3 | |
| Gene Description | Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (GluA3) | |
| Gene Name in Paper | GRIA3 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000541091 ENST00000620443 ENST00000622768 | |
| UniProt ID | P42263 | |
| Entrez Gene ID | 2892 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |