RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06713 |
| Gene Symbol | TF3B | |
| Gene Description | Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B-related factor 1) (BRF-1) (hBRF) (TAF3B2) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2) | |
| Gene Name in Paper | TF3B | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000327359 ENST00000379937 ENST00000392557 ENST00000440513 ENST00000446501 ENST00000547530 ENST00000548421 | |
| UniProt ID | Q92994 | |
| Entrez Gene ID | 2972 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |