Vhf06700 details

Gene vhfRNAi AccessionVhf06700
Gene SymbolZN540
Gene DescriptionZinc finger protein 540
Gene Name in PaperZN540
GroupHost Factor
Ensembl Gene IDENST00000316433 ENST00000343599 ENST00000589117 ENST00000592533 
UniProt IDQ8NDQ6
Entrez Gene ID163255
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)