RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06669 |
| Gene Symbol | MOC2A | |
| Gene Description | Molybdopterin synthase sulfur carrier subunit (MOCO1-A) (Molybdenum cofactor synthesis protein 2 small subunit) (Molybdenum cofactor synthesis protein 2A) (MOCS2A) (Molybdopterin-synthase small subunit) (Sulfur carrier protein MOCS2A) | |
| Gene Name in Paper | MOC2A | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000361377 ENST00000450852 ENST00000508922 ENST00000510818 ENST00000582677 ENST00000584946 | |
| UniProt ID | O96033 | |
| Entrez Gene ID | 4338 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |